A low-noise multi-electrode array system for
in vitro extracellular electrophysiology

The MED64 is a user-friendly multi-electrode array (MEA) system for stimulation and recording of field potentials (extracellular signals) from different areas within a biological sample over hours, days, weeks and even months. Acute or cultured biological preparations are placed or grown directly on a grid of 64 planar microelectrodes, which serve a dual purpose of stimulus-delivery and signal recording. The unique construction of the system eliminates the need for many cumbersome and expensive equipment used in conventional electrophysiology, including a faraday cage, anti-vibration table, micromanipulators, and even the puller and glass microelectrodes. Learn MORE




Safety Pharmacology Society, 14th Annual Meeting
Washington DC, Oct. 19-21, Booth# 406

Neuroscience 2014
Washington DC, Nov.16-19. Booth# 2636

Updated 10/06/2014

New Products

Mobius New Spike Sorter
Now available!

Updated 08/05/2014

Medium throughput system with multi-wells, Ideal for drug testing with stem cell-derived cardiomyocytes/neurons.

MED64-Quad II
Medium throughput system , ideal for drug testing with acute tissue samples.

Updated 11/27/2013

New Publications

Image-based evaluation of contraction-relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology.
Hayakawa T, et el., J Mol Cell Cardiol.

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease.
Fu AK, et el., Proc Natl Acad Sci U S A.  

Updated 10/06/2014

New Document

Application Note
 - Human Stem Cell-derived Cardiomyocytes-

Protocol for the Cellectis hES-CMCTM is now added.
Updated 09/06/13

Mobius Tutorial (MED-A64MD1)
Chapter 4, Mobius QT is updated based on the new workflow templates. 
Updated 06/27/13




• Evoked and spontaneous activities (fEPSP, Spikes)
• Synaptic plasticity (LTP, LTD)
• Spontaneous rhythmic activities (oscillations)
• Pacing and propagation in myocytes
• Safety pharmacology (FPD prolongation / CNS toxicology)
• Drug testing with acute tissue slices
• Chronic drug testing with cultures
• Stem cell biology


Copyright: 2010 Alpha MED Scientific Inc
Alpha MED Scientific Inc., 209 Saito-incubator, 7-7-15, Saito-asagi, Ibaraki Osaka, 567-0085, Japan