Hippocampus 2020-09-08T00:34:25+00:00

Acute Tissue Slices / Hippocampus

Age-related cognitive impairment: Role of reduced synaptobrevin-2 levels in memory and synaptic plasticity deficits.
Orock A, Logan S, Deak F.
J Gerontol A Biol Sci Med Sci. 2019 Jan 14.

Prenatal exposure to PCBs in Cyp1a2 knock-out mice interferes with F1 fertility, impairs long-term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects.
Hufgard JR, Sprowles JLN, Pitzer EM, Koch SE, Jiang M, Wang Q, Zhang X, Biesiada J, Rubinstein J, Puga A, Williams MT, Vorhees CV.
J Appl Toxicol. 2018 Dec 18.

New role of P2X7 receptor in an Alzheimer’s disease mouse model
Martin E, Amar M, Dalle C, Youssef I, Boucher C, Le Duigou C, Brückner M, Prigent A, Sazdovitch V, Halle A, Kanellopoulos JM, Fontaine B, Delatour B, Delarasse C.
Mol Psychiatry.  2018 Jun 22. doi: 10.1038.

Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse.
Xiang Z, Bao Y, Zhang J, Liu C, Xu D, Liu F, Chen H, He L, Ramakrishna S, Zhang Z, Vardi N, Xu Y.
Neuropharmacology. 2018 Sep 1;139:137-149.

Electrophysiological characteristics of hippocampal postnatal early development mediated by AMPA receptors in rats.
Chen XY, Zhang AF, Zhao W, Gao YD, Duan HM, Hao P, Yang ZY, Li XG.
Cheng Li Xue Bao. 2018 Apr 25;70(2):106-114.

CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer’s Disease.
Shentu YP, Huo Y, Feng XL, Gilbert J, Zhang Q, Liuyang ZY, Wang XL, Wang G, Zhou H, Wang XC, Wang JZ, Lu YM, Westermarck J, Man HY, Liu R.
Cell Rep. 2018 Jul 17;24(3):713-723.

A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer’s Disease.
Wang X, Liu D, Huang HZ, Wang ZH, Hou TY, Yang X, Pang P, Wei N, Zhou YF, Dupras MJ, Calon F, Wang YT, Man HY, Chen JG, Wang JZ, Hébert SS, Lu Y, Zhu LQ.
Biol Psychiatry. 2018 Mar 1;83(5):395-405.

Zinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer’s disease.
Lee MC, Yu WC, Shih YH, Chen CY, Guo ZH, Huang SJ, Chan JCC, Chen YR.
Sci Rep. 2018 Mar 19;8(1):4772.

Memantine improves outcomes after repetitive traumatic brain injury.
Mei Z, Qiu J, Alcon S, Hashim J, Rotenberg A, Sun Y, Meehan WP 3rd, Mannix R.
Behav Brain Res. 2018 Mar 15;340:195-204.

Adenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders.
Warren TJ, Simeone TA, Smith DD, Grove R, Adamec J, Samson KK, Roundtree HM, Madhavan D, Simeone KA.
Neurobiol Dis. 2018 Feb 27;114:45-52.

Increased GSNOR Expression during Aging Impairs Cognitive Function and Decreases S-Nitrosation of CaMKIIα.
Zhang Y, Wu K, Su W, Zhang DF, Wang P, Qiao X, Yao Q, Yuan Z, Yao YG, Liu G, Zhang C, Liu L, Chen C.
J Neurosci. 2017 Oct 4;37(40):9741-9758

Fluoxetine administration during adolescence attenuates cognitive and synaptic deficits in adult 3×TgAD mice.
Sun DS, Gao LF, Jin L, Wu H, Wang Q, Zhou Y, Fan S, Jiang X, Ke D, Lei H, Wang JZ, Liu GP.
Neuropharmacology. 2017 Nov;126:200-212.

Conditioned place preference training prevents hippocampal depotentiation in an orexin-dependent manner.
Lu GL, Yau HJ, Chiou LC.
J Biomed Sci. 2017 Sep 6;24(1):69.

Gamma rhythm low field magnetic stimulation alleviates neuropathologic changes and rescues memory and cognitive impairments in a mouse model of Alzheimer’s disease.
Zhen J, Qian Y, Weng X, Su W, Zhang J, Cai L, Dong L, An H, Su R, Wang J, Zheng Y, Wang X.
Alzheimers Dement (N Y). 2017 Sep 11;3(4):487-497

Neural repair by NT3-chitosan via enhancement of endogenous neurogenesis after adult focal aspiration brain injury.
Hao P, Duan H, Hao F, Chen L, Sun M, Fan KS, Sun YE, Williams D, Yang Z, Li X.
Biomaterials. 2017 Sep;140:88-102.

Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice.
Leon J, Moreno AJ, Garay BI, Chalkley RJ, Burlingame AL, Wang D, Dubal DB.
Cell Rep. 2017 Aug 8;20(6):1360-1371.

Effects of M1 and M4 activation on excitatory synaptic transmisson in CA1.
Thorn C, Popiolek M, Stark E, Edgerton J.
Hippocampus. 2017 Apr 19. doi: 10.1002/hipo.22732

Clinical-grade human umbilical cord-derived mesenchymal stem cells reverse cognitive aging via improving synaptic plasticity and endogenous neurogenesis.
Cao N, Liao T, Liu J, Fan Z, Zeng Q, Zhou J, Pei H, Xi J, He L, Chen L, Nan X, Jia Y, Yue W, Pei X.
Cell Death Dis. 2017 Aug 10;8(8):e2996

Cdk5-dependent phosphorylation of liprinα1 mediates neuronal activity-dependent synapse development.
Huang H, Lin X, Liang Z, Zhao T, Du S, Loy MMT, Lai KO, Fu AKY, Ip NY.
Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6992-E7001

Reduction of long-term potentiation at Schaffer collateral-CA1 synapses in the rat hippocampus at the acute stage of vestibular compensation.
Lee GW, Kim JH, Kim MS.
Korean J Physiol Pharmacol. 2017 Jul;21(4):423-428

Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model.
Chai GS, Feng Q, Wang ZH, Hu Y, Sun DS, Li XG, Ke D, Li HL, Liu GP, Wang JZ.
Mol Neurodegener. 2017 May 4;12(1):34.

Caffeine Increases Hippocampal Sharp Waves in Vitro.
Watanabe Y, Ikegaya Y.
Biol Pharm Bull. 2017;40(7):1111-1115

NETO1 Guides Development of Glutamatergic Connectivity in the Hippocampus by Regulating Axonal Kainate Receptors.
Orav E, Atanasova T, Shintyapina A, Kesaf S, Kokko M, Partanen J, Taira T, Lauri SE.
eNeuro. 2017 Jul 3;4(3). pii: ENEURO.0048-17.2017.

Paternal spatial training enhances offspring’s cognitive performance and synaptic plasticity in wild-type but not improve memory deficit in Alzheimer’s mice.
Zhang S, Li X, Wang Z, Liu Y, Gao Y, Tan L, Liu E, Zhou Q, Xu C, Wang X, Liu G, Chen H, Wang JZ.
Sci Rep. 2017 May 8;7(1):1521.

Memantine improves outcomes after repetitive traumatic brain injury.
Mei Z, Qiu J, Alcon S, Hashim J, Rotenberg A, Sun Y, Meehan WP 3rd, Mannix R.
Behav Brain Res. 2017 Apr 12. pii: S0166-4328(17)30621-6. doi: 10.1016/j.bbr.2017.04.017

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease.
Nobili A, Latagliata EC, Viscomi MT, Cavallucci V, Cutuli D, Giacovazzo G, Krashia P, Rizzo FR, Marino R, Federici M, De Bartolo P, Aversa D, Dell’Acqua MC, Cordella A, Sancandi M, Keller F, Petrosini L, Puglisi-Allegra S, Mercuri NB, Coccurello R, Berretta N, D’Amelio M.
Nat Commun. 2017 Apr 3;8:14727. doi: 10.1038/ncomms1472

A maternal diet high in saturated fat impairs offspring hippocampal function in a sex-specific manner.
Robb JL, Messa I, Lui E, Yeung D, Thacker J, Satvat E, Mielke JG.
Behav Brain Res. 2017 Mar 1;326:187-199. doi: 10.1016/j.bbr.2017.02.049.

Astrocyte lipid metabolism is critical for synapse development and function in vivo. 
Van Deijk AF, Camargo N, Timmerman J, Heistek T, Brouwers JF, Mogavero F, Mansvelder HD, Smit AB, Verheijen MH.
Glia. 2017 Feb 7. doi: 10.1002/glia.23120.

Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory.
Amos-Kroohs RM, Davenport LL, Atanasova N, Abdulla ZI, Skelton MR, Vorhees CV, Williams MT.
Neurotoxicol Teratol. 2017 Jan – Feb;59:16-26. doi: 10.1016

A heterozygous mutation in tubulin, beta 2B ( Tubb2b ) causes cognitive deficits and hippocampal disorganization.
Stottmann RW, Driver A, Gutierrez A, Skelton MR, Muntifering M, Stepien C, Knudson L, Kofron M, Vorhees CV, Williams MT.
Genes Brain Behav. 2017 Feb;16(2):250-259. doi: 10.1111

ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion.
Li WG, Liu MG, Deng S, Liu YM, Shang L, Ding J, Hsu TT, Jiang Q, Li Y, Li F, Zhu MX, Xu TL.
Nat Commun. 2016 Dec 7;7:13770.

Inositol Phosphate Accumulation in Vivo Provides a Measure of Muscarinic M Receptor Activation.
Popiolek M, Nguyen DP, Reinhart V, Edgerton JR, Harms J, Lotarski SM, Steyn SJ, Davoren JE, Grimwood S.
Biochemistry. 2016 Dec 27;55(51):7073-7085. doi: 10.1021/acs.biochem.6b00688

Functional hyaluronate collagen scaffolds induce NSCs differentiation into functional neurons in repairing the traumatic brain injury.
Duan H, Li X, Wang C, Hao P, Song W, Li M, Zhao W, Gao Y, Yang Z.
Acta Biomater. 2016 Nov;45:182-195. doi: 10.1016/j.actbio.2016.08.043

The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines.
Liang Z, Zhan Y, Shen Y, Wong CC, Yates JR 3rd, Plattner F, Lai KO, Ip NY.
Nat Commun. 2016 Oct 31;7:13282.

Hippocampal Activation of Rac1 Regulates the Forgetting of Object Recognition Memory.
Liu Y, Du S, Lv L, Lei B, Shi W, Tang Y, Wang L, Zhong Y.
Curr Biol. 2016 Sep 12;26(17):2351-7. doi: 10.1016/j.cub.2016.06.056

Dexmedetomidine promotes the recovery of the field excitatory postsynaptic potentials (fEPSPs) in rat hippocampal slices exposed to oxygen-glucose deprivation.
Kim SE, Ko IG, Kim CJ, Chung JY, Yi JW, Choi JH, Jang MS, Han JH.
Neurosci Lett. 2016 Sep 19;631:91-6. doi: 10.1016/j.neulet.2016.08.033

Opposite monosynaptic scaling of BLP-vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory.
Yang Y, Wang ZH, Jin S, Gao D, Liu N, Chen SP, Zhang S, Liu Q, Liu E, Wang X, Liang X, Wei P, Li X, Li Y, Yue C, Li HL, Wang YL, Wang Q, Ke D, Xie Q, Xu F, Wang L, Wang JZ.
Nat Commun. 2016 Jul 14;7:11935. doi: 10.1038/ncomms11935

Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling.
Yin Y, Gao D, Wang Y, Wang ZH, Wang X, Ye J, Wu D, Fang L, Pi G, Yang Y, Wang XC, Lu C, Ye K, Wang JZ.
Proc Natl Acad Sci U S A. 2016 Jun 13. pii: 201604519.

Long-term Ameliorative Effects of the Antidepressant Fluoxetine Exposure on Cognitive Deficits in 3 × TgAD Mice.
Jin L, Gao LF, Sun DS, Wu H, Wang Q, Ke D, Lei H, Wang JZ, Liu GP.
Mol Neurobiol. 2016 Jun 21

High-frequency electroacupuncture evidently reinforces hippocampal synaptic transmission in Alzheimer’s disease rats.
Li W, Kong LH, Wang H, Shen F, Wang YW, Zhou H, Sun GJ.
Neural Regen Res. 2016 May;11(5):801-6. doi: 10.4103/1673-5374.182708.

IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline.
Fu AK, Hung KW, Yuen MY, Zhou X, Mak DS, Chan IC, Cheung TH, Zhang B, Fu WY, Liew FY, Ip NY.
Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2705-13

Intrinsic Cornu Ammonis Area 1 Theta-Nested Gamma Oscillations Induced by Optogenetic Theta Frequency Stimulation.
Butler JL, Mendonça PR, Robinson HP, Paulsen O.
J Neurosci. 2016 Apr 13;36(15):4155-69. doi: 10.1523/JNEUROSCI.3150-15.2016

Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms.
Liu MG, Li HS, Li WG, Wu YJ, Deng SN, Huang C, Maximyuk O, Sukach V, Krishtal O, Zhu MX, Xu TL.
Sci Rep. 2016 Mar 21;6:23350. doi: 10.1038/srep23350.

Orexin A induces bidirectional modulation of synaptic plasticity: Inhibiting long-term potentiation and preventing depotentiation
Lu GL, Lee CH, Chiou LC.
Neuropharmacology. 2016 Mar 7. pii: S0028-3908(16)30075-2.

Transient Receptor Potential-canonical 1 is Essential for Environmental Enrichment-Induced Cognitive Enhancement and Neurogenesis.
Du LL, Wang L, Yang XF, Wang P, Li XH, Chai DM, Liu BJ, Cao Y, Xu WQ, Liu R, Tian Q, Wang JZ, Zhou XW.Mol
. 2016 Feb 24. [Epub ahead of print]

Claustrum: a case for directional, excitatory, intrinsic connectivity in the rat.
Orman R.
J Physiol Sci. 2015 Nov;65(6):533-44.

Critical Role of Endoplasmic Reticulum Stress in Chronic Intermittent Hypoxia-Induced Deficits in Synaptic Plasticity and Long-Term Memory.
Xu Lin-Hao, Xie Hui, Shi Zhi-Hui, Du Li-Da, Wing Yun-Kwok, Li Albert M., Ke Ya, and Yung Wing-Ho.
Antioxid Redox Signal. 2015 Sep 20;23(9):695-710.

Activation of Glycogen Synthase Kinase-3 Mediates the Olfactory Deficit-Induced Hippocampal Impairments.
Hu J, Huang HZ, Wang X, Xie AJ, Wang X, Liu D, Wang JZ, Zhu LQ.
Mol Neurobiol. 2015 Dec;52(3):1601-17

Anti-diabetes drug pioglitazone ameliorates synaptic defects in AD transgenic mice by inhibiting cyclin-dependent kinase5 activity.
Chen J, Li S, Sun W, Li J.
PLoS One. 2015 Apr 14;10(4):e0123864.

Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice.
Jiang X, Chai GS, Wang ZH, Hu Y, Li XG, Ma ZW, Wang Q, Wang JZ, Liu GP.
Sci Rep. 2015 Mar 30;5:9488.

CaMKII-dependent dendrite ramification and spine generation promote spatial training-induced memory improvement in a rat model of sporadic Alzheimer’s disease.
Jiang X, Chai GS, Wang ZH, Hu Y, Li XG, Ma ZW, Wang Q, Wang JZ, Liu GP.
Neurobiol Aging. 2015 Feb;36(2):867-76.

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease.
Fu AK, Hung KW, Huang H, Gu S, Shen Y, Cheng EY, Ip FC, Huang X, Fu WY, Ip NY.
Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9959-64.

Magnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer’s model.
Xu ZP, Li L, Bao J, Wang ZH, Zeng J, Liu EJ, Li XG, Huang RX, Gao D, Li MZ, Zhang Y, Liu GP, Wang JZ.
PLoS One. 2014 Sep 30;9(9):e108645

Magnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer’s model.
Xu ZP, Li L, Bao J, Wang ZH, Zeng J, Liu EJ, Li XG, Huang RX, Gao D, Li MZ, Zhang Y, Liu GP, Wang JZ.
PLoS One. 2014 Sep 30;9(9):e108645

Isoflurane impairs learning and hippocampal long-term potentiation via the saturation of synaptic plasticity.
Uchimoto K, Miyazaki T, Kamiya Y, Mihara T, Koyama Y, Taguri M, Inagawa G, Takahashi T, Goto T.
Anesthesiology. 2014 Aug, 121, 302-12.

Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer’s disease.
Vegh MJ, Heldring CM, Kamphuis W, Hijazi S, Timmerman AJ, Li K, van Nierop P, Mansvelder HD, Hol EM, Smit AB, van Kesteren RE.
Acta. Neuropathol. Commun. 2014 Jul, 2, 76.

In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1α knockout mice.
Simeone TA, Samson KK, Matthews SA, Simeone KA.
Epilepsia, 2014 May, 55, e44-9.

(28)Silicon radiation-induced enhancement of synaptic plasticity in the hippocampus of naive and cognitively tested mice.
Raber J, Rudobeck E, Campbell-Beachler M, Allen AR, Allen B, Rosi S, Nelson GA, Ramachandran S, Turner J, Fike JR, Vlkolinsky R.
Radiat. Res. 2014 Apr, 181, 362-8.

Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures.
Simeone KA, Matthews SA, Samson KK, Simeone TA.
Exp. Neurol. 2014 Jan, 251, 84-90.

Amyloid 25–35 induces impairment of cognitive function and long-term potentiation through phosphorylation of collapsin response mediator protein 2.
Isono T, Yamashitaa N, Obara M, Arakia T, Nakamura F, Kamiya Y, Alkam T, Nitta A ,Nabeshima T, Mikoshibaf K, Ohshima T, Goshima Y.
Neurosci Res. 2013 Nov;77(3):180-5.

ProNGFNGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice.
Tiveron C, Fasulo L, Capsoni S, Malerba F, Marinelli S, Paoletti F, Piccinin S, Scardigli R, Amato G, Brandi R, Capelli P, D’Aguanno S, Florenzano F, La Regina F, Lecci A, Manca A, Meli G, Pistillo L, Berretta N, Nisticò R, Pavone F, Cattaneo A.
Cell Death Differ. 2013 Aug;20(8):1017-30.

Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices.
Simeone TA, Simeone KA, Samson KK, Kim DY, Rho JM.
Neurobiol Dis. 2013 Jun;54:68-81.

Bisphenol A significantly modulates long-term depression in the hippocampus as observed by multi-electrode system.
Hasegawa Y , Ogiue-Ikeda M, Tanabe N, Kimoto T, Hojo Y, Yamazaki T, Kawato S.
Neuro Endocrinol Lett. 2013 ;34(2):129-34.

α2-containing GABAA receptors expressed in hippocampal region CA3 control fast network oscillations.
Heistek TS, Ruiperez-Alonso M, Timmerman AJ, Brussaard AB, Mansvelder HD.
J Physiol. 2013 Feb 15;591(Pt 4):845-58.

Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis.
Nisticò R, Mango D, Mandolesi G, Piccinin S, Berretta N, Pignatelli M, Feligioni M, Musella A, Gentile A, Mori F, Bernardi G, Nicoletti F, Mercuri NB, Centonze D.
PLoS One. 2013;8(1):e54666.

Astrocytic Ca2+ signals are required for the functional integrity of tripartite synapses.
anaka M, Shih PY, Gomi H, Yoshida T, Nakai J, Ando R, Furuichi T, Mikoshiba K, Semyanov A, Itohara S.
Mol Brain. 2013 Jan 28;6:6.

Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism.
Shen Y, Fu WY, Cheng EY, Fu AK, Ip NY.
J Neurosci. 2013 Jan 9;33(2):464-72.

TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory.
Lai KO, Wong AS, Cheung MC, Xu P, Liang Z, Lok KC, Xie H, Palko ME, Yung WH, Tessarollo L, Cheung ZH, Ip NY.
Nat Neurosci. 2012 Nov;15(11):1506-15.

Modulation of synaptic plasticity in the hippocampus by hippocampus-derived estrogen and androgen.
Ooishi Y, Kawato S, Hojo Y, Hatanaka Y, Higo S, Murakami G, Komatsuzaki Y, Ogiue-Ikeda M, Kimoto T, Mukai H.
J. Steroid Biochem. Mol. Biol. 2012 Aug, 131, 37-51.

Post-weaning mice fed exclusively milk have deficits in induction of long-term depression in the CA1 hippocampal region and spatial learning and memory.
Nishie H, Miyata R, Fujikawa R, Kinoshita KI, Muroi Y, Ishii T.
Neurosci Res. 2012 Aug;73(4):292-301.

M2 muscarinic acetylcholine receptors regulate long-term potentiation at hippocampal CA3 pyramidal cell synapses in an input-specific fashion.
Zheng F, Wess J, Alzheimer C.
J Neurophysiol. 2012 Jul;108(1):91-100.

(-)Clausenamide facilitates synaptic transmission at hippocampal Schaffer collateral-CA1 synapses.
Ning N, Hu JF, Sun JD, Han N, Zhang JT, Chen NH.
Eur J Pharmacol. 2012 May 5;682(1-3):50-5.

Hippocampus versus entorhinal cortex decoupling by an NR2 subunit-specific block of NMDA receptors in a rat in vitro model of temporal lobe epilepsy.
Berretta N, Ledonne A, Mango D, Bernardi G, Mercuri NB.
Epilepsia. 2012 May;53(5):e80-4.

CMOS image sensor integrated with micro-LED and multielectrode arrays for the patterned photostimulation and multichannel recording of neuronal tissue.
Nakajima A, Kimura H, Sawadsaringkarn Y, Maezawa Y, Kobayashi T, Noda T, Sasagawa K, Tokuda T, Ishikawa Y,Shiosaka S, Ohta J.
Opt Express. 2012 Mar 12;20(6):6097-108.

Counteracting roles of metabotropic glutamate receptor subtypes 1 and 5 in regulation of pain-related spatial and temporal synaptic plasticity in rat entorhinal-hippocampal pathways.
Liu MG, Lu D, Wang Y, Chen XF, Li Z, Xu Y, Jin JH, Wang RR, Chen J.
Neurosci Lett. 2012 Jan 17;507(1):38-42.

Acute hippocampal slice preparation and hippocampal slice cultures.
Lein PJ, Barnhart CD, Pessah IN.
Methods Mol Biol. 2011;758:115-34.

Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo.
Kim KH, Pessah IN.
Neurotoxicology. 2011 Dec;32(6):981-5.

Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity.
Hojo Y, Higo S, Kawato S, Hatanaka Y, Ooishi Y, Murakami G, Ishii H, Komatsuzaki Y, Ogiue-Ikeda M, Mukai H, Kimoto T.
Front Endocrinol (Lausanne). 2011 Oct 10;2:43.

In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes.
Curran CP, Nebert DW, Genter MB, Patel KV, Schaefer TL, Skelton MR, Williams MT, Vorhees CV.
Environ Health Perspect. 2011 Sep;119(9):1286-93.

Fast network oscillations in vitro exhibit a slow decay of temporal auto-correlations.
Poil SS, Jansen R, van Aerde K, Timmerman J, Brussaard AB, Mansvelder HD, Linkenkaer-Hansen K.
Eur J Neurosci. 2011 Aug;34(3):394-403.

Planar Multielectrode Array Coupled Complementary Metal Oxide Semiconductor Image Sensor for In vitro Electrophysiology.
Nakajima A, Noda T, Sasagawa K, Tokuda T, Ishikawa Y, Shiosaka S, Ohta J.
Jpn J Appl Phys. 2011 Apr;50(4):04DL04.

Differential roles of ERK, JNK and p38 MAPK in pain-related spatial and temporal enhancement of synaptic responses in the hippocampal formation of rats: multi-electrode array recordings.
Liu MG, Wang RR, Chen XF, Zhang FK, Cui XY, Chen J.
Brain Res. 2011 Mar 25;1382:57-69.

Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.
Alberi L, Liu S, Wang Y, Badie R, Smith-Hicks C, Wu J, Pierfelice TJ, Abazyan B, Mattson MP, Kuhl D, Pletnikov M, Worley PF, Gaiano N.
Neuron. 2011 Feb 10;69(3):437-44.

mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway.
Chen HH, Liao PF, Chan MH.
J Biomed Sci. 2011 Feb 22;18:19.

Modulation of synaptic plasticity by brain estrogen in the hippocampus.
Mukai H, Kimoto T, Hojo Y, Kawato S, Murakami G, Higo S, Hatanaka Y, Ogiue-Ikeda M.
Biochim Biophys Acta. 2010 Oct;1800(10):1030-44.

Brain-derived neurotrophic factor rescues and prevents chronic intermittent hypoxia-induced impairment of hippocampal long-term synaptic plasticity.
Xie H, Leung KL, Chen L, Chan YS, Ng PC, Fok TF, Wing YK, Ke Y, Li AM, Yung WH.
Neurobiol Dis. 2010 Oct;40(1):155-62.

BACE1 deficiency causes altered neuronal activity and neurodegeneration.
Hu X, Zhou X, He W, Yang J, Xiong W, Wong P, Wilson CG, Yan R.
J Neurosci. 2010 Jun 30;30(26):8819-29.

Neural circuits and temporal plasticity in hindlimb representation of rat primary somatosensory cortex: revisited by multi-electrode array on brain slices.
Wang DD, Li Z, Chang Y, Wang RR, Chen XF, Zhao ZY, Cao FL, Jin JH, Liu MG, Chen J.
Neurosci Bull. 2010 Jun;26(3):175-87.

GABAergic synapse properties may explain genetic variation in hippocampal network oscillations in mice.
Heistek TS, Jaap Timmerman A, Spijker S, Brussaard AB, Mansvelder HD.
Front Cell Neurosci. 2010 Jun 2;4:18.

Diazoxide reduces status epilepticus neuron damage in diabetes.
Huang CW, Wu SN, Cheng JT, Tsai JJ, Huang CC.
Neurotox Res. 2010 May;17(4):305-16.

Modeling action potential generation during single and dual electrode stimulation of CA3 axons in hippocampal slice.
Bellinger SC, Rho JM, Steinmetz PN.
Comput Biol Med. 2010 May;40(5):487-97.

Priming of hippocampal population bursts by individual perisomatic-targeting interneurons.
Ellender TJ, Nissen W, Colgin LL, Mann EO, Paulsen O.
J Neurosci. 2010 Apr 28;30(17):5979-91.

Effects of eicosapentaenoic acid on synaptic plasticity, fatty acid profile and phosphoinositide 3-kinase signaling in rat hippocampus and differentiated PC12 cells.
Kawashima A, Harada T, Kami H, Yano T, Imada K, Mizuguchi K.
J Nutr Biochem. 2010 Apr;21(4):268-77.

Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits.
Sun Y, Liou B, Ran H, Skelton MR, Williams MT, Vorhees CV, Kitatani K, Hannun YA, Witte DP, Xu YH, Grabowski GA.
Hum Mol Genet. 2010 Mar 15;19(6):1088-97.

Permissive role of insulin in the expression of long-term potentiation in the hippocampus of immature rats.
Zhao W, Wu X, Xie H, Ke Y, Yung WH.
Neurosignals. 2010;18(4):236-45.

Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse.
Sun Y, Ran H, Zamzow M, Kitatani K, Skelton MR, Williams MT, Vorhees CV, Witte DP, Hannun YA, Grabowski GA.
Hum Mol Genet. 2010 Feb 15;19(4):634-47.

Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice.
Delotterie D, Ruiz G, Brocard J, Schweitzer A, Roucard C, Roche Y, Suaud-Chagny MF, Bressand K, Andrieux A.
Psychopharmacology (Berl). 2010 Jan;208(1):131-41.

Piccolo knockdown-induced impairments of spatial learning and long-term potentiation in the hippocampal CA1 region.
Ibi D, Nitta A, Ishige K, Cen X, Ohtakara T, Nabeshima T, Ito Y.
Neurochem Int. 2010 Jan;56(1):77-83.

Differential effects of long and short train theta burst stimulation on LTP induction in rat anterior cingulate cortex slices: multi-electrode array recordings.
He Y, Liu MG, Gong KR, Chen J.
Neurosci Bull. 2009 Oct;25(5):309-18.

Nociception-induced spatial and temporal plasticity of synaptic connection and function in the hippocampal formation of rats: a multi-electrode array recording.
Zhao XY, Liu MG, Yuan DL, Wang Y, He Y, Wang DD, Chen XF, Zhang FK, Li H, He XS, Chen J.
Mol Pain. 2009 Sep 22;5:55.

Protective effect of S14G-humanin against beta-amyloid induced LTP inhibition in mouse hippocampal slices.
Zhang W, Miao J, Hao J, Li Z, Xu J, Liu R, Cao F, Wang R, Chen J, Li Z.
Peptides. 2009 Jun;30(6):1197-202.

Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.
Hawasli AH, Koovakkattu D, Hayashi K, Anderson AE, Powell CM, Sinton CM, Bibb JA, Cooper DC.
PLoS One. 2009 Jun 4;4(6):e5808.

Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation.
Kim KH, Inan SY, Berman RF, Pessah IN.
Toxicol Appl Pharmacol. 2009 Jun 1;237(2):168-77.

Effects of bupivacaine and ropivacaine on field potential in rat hippocampal slices.
Yi JW, Lee BJ, Kim DO, Park SW, Choi YK, Chang HK, Kim CJ, Park JH.
Br J Anaesth. 2009 May;102(5):673-9.

X11-like protein deficiency is associated with impaired conflict resolution in mice.
Sano Y, Ornthanalai VG, Yamada K, Homma C, Suzuki H, Suzuki T, Murphy NP, Itohara S.
J Neurosci. 2009 May 6;29(18):5884-96.

Maintaining network activity in submerged hippocampal slices: importance of oxygen supply.
Hájos N, Ellender TJ, Zemankovics R, Mann EO, Exley R, Cragg SJ, Freund TF, Paulsen O.
Eur J Neurosci. 2009 Jan;29(2):319-27.

Diabetic hyperglycemia aggravates seizures and status epilepticus-induced hippocampal damage.
Huang CW, Cheng JT, Tsai JJ, Wu SN, Huang CC.
Neurotox Res. 2009 Jan;15(1):71-81.

Broadening of activity with flow across neural structures.
Lytton WW, Orman R, Stewart M.
Perception. 2008;37(3):401-7.

Local axon collaterals of area CA1 support spread of epileptiform discharges within CA1, but propagation is unidirectional.
Orman R,Von Gizycki H,Lytton WW,Stewart M.
Hippocampus. 2008 Oct;18(10):1021-33.

Estrogen synthesis in the brain–role in synaptic plasticity and memory.
Hojo Y, Murakami G, Mukai H, Higo S, Hatanaka Y, Ogiue-Ikeda M, Ishii H, Kimoto T, Kawato S.
Mol Cell Endocrinol. 2008 Aug 13;290(1-2):31-43.

Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice.
Sun Y, Witte DP, Ran H, Zamzow M, Barnes S, Cheng H, Han X, Williams MT, Skelton MR, Vorhees CV, Grabowski GA.
Hum Mol Genet. 2008 Aug 1;17(15):2345-56.

Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PSldE9 mouse model of Alzheimer’s disease.
Goto Y, Niidome T, Hongo H, Akaike A, Kihara T, Sugimoto H.
Eur J Pharmacol. 2008 Mar 31;583(1):84-91.

Synaptic activity and triphenyltetrazolium chloride metabolism are correlated after oxygen-glucose deprivation in acute, but not cultured, hippocampal slices.
Mielke JG, Comas T, Ahuja T, Preston E, Mealing GA.
Brain Res. 2007 Oct 24;1176:113-23.

Local production of sex hormones and their modulation of hippocampal synaptic plasticity.
Ishii H, Tsurugizawa T, Ogiue-Ikeda M, Asashima M, Mukai H, Murakami G, Hojo Y, Kimoto T, Kawato S.
Neuroscientist. 2007 Aug;13(4):323-34.

Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation.
Wu Y, Liang S, Oda Y, Ohmori I, Nishiki T, Takei K, Matsui H, Tomizawa K.
EMBO J. 2007 Jun 20;26(12):2981-90.

Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.
Hu X, Shi Q, Zhou X, He W, Yi H, Yin X, Gearing M, Levey A, Yan R.
EMBO J. 2007 Jun 6;26(11):2755-67.

Rapid modulation of synaptic plasticity by estrogens as well as endocrine disrupters in hippocampal neurons.
Ogiue-Ikeda M, Tanabe N, Mukai H, Hojo Y, Murakami G, Tsurugizawa T, Takata N, Kimoto T, Kawato S.
Brain Res Rev. 2008 Mar;57(2):363-75.

Glucose and hippocampal neuronal excitability: role of ATP-sensitive potassium channels.
Huang CW, Huang CC, Cheng JT, Tsai JJ, Wu SN.
J Neurosci Res. 2007 May 15;85(7):1468-77.

Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons.
Mukai H, Tsurugizawa T, Murakami G, Kominami S, Ishii H, Ogiue-Ikeda M, Takata N, Tanabe N, Furukawa A, Hojo Y, Ooishi Y, Morrison JH, Janssen WG, Rose JA, Chambon P, Kato S, Izumi S, Yamazaki T, Kimoto T, Kawato S.
J Neurochem. 2007 Feb;100(4):950-67.

Role of cytochrome p450 in synaptocrinology: endogenous estrogen synthesis in the brain hippocampus.
Murakami G, Tanabe N, Ishii HT, Ogiue-Ikeda M, Tsurugizawa T, Mukai H, Hojo Y, Takata N, Furukawa A, Kimoto T, Kawato S.
Drug Metab Rev. 2006;38(3):353-69.

Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 mice.
Mielke JG, Nicolitch K, Avellaneda V, Earlam K, Ahuja T, Mealing G, Messier C.
Behav Brain Res. 2006 Dec 15;175(2):374-82.

Local neurosteroid production in the hippocampus: influence for synaptic plasticity of memory.
Mukai H, Tsurugizawa T, Ogiue-Ikeda M, Murakami G, Hojo Y, Ishii H, Kimoto T, Kawato S.
Neuroendocrinology. 2006;84(4):255-63.

Transgenic mice expressing dominant-negative activin receptor IB in forebrain neurons reveal novel functions of activin at glutamatergic synapses.
Müller MR, Zheng F, Werner S, Alzheimer C.
J Biol Chem. 2006 Sep 29;281(39):29076-84.

Differential modulation by the GABAB receptor allosteric potentiator 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)-phenol (CGP7930) of synaptic transmission in the rat hippocampal CA1 area.
Chen Y, Menendez-Roche N, Sher E.
J Pharmacol Exp Ther. 2006 Jun;317(3):1170-7.

Dephosphorylation and internalization of cell adhesion molecule L1 induced by theta burst stimulation in rat hippocampus.
Itoh K, Shimono K, Lemmon V.
Mol Cell Neurosci 2005 Jun;29(2):245-9.

Serotonergic modulation of carbachol-induced rhythmic activity in hippocampal slices.
Krause M, Jia Y.
Neuropharmacology 2005 Mar;48(3):381-90.

Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitro.
Mann EO, Suckling JM, Hajos N, Greenfield SA, Paulsen O.
Neuron. 2005 Jan 6;45(1):105-17.

Hippocampal gamma-frequency oscillations: from interneurones to pyramidal cells, and back.
Mann EO,Radcliffe CA, Paulsen O.
J Physiol. 2005 Jan 1;562(Pt 1):55-63.

Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro.
Hajos N, Palhalmi J, Mann EO, Nemeth B, Paulsen O, Freund TF.
J Neurosci. 2004 Oct 13;24(41):9127-37.

Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.
Nakatsu F, Okada M, Mori F, Kumazawa N, Iwasa H, Zhu G, Kasagi Y, Kamiya H, Harada A, Nishimura K, Takeuchi A, Miyazaki T, Watanabe M, Yuasa S, Manabe T, Wakabayashi K, Kaneko S, Saito T, Ohno H.
J Cell Biol. 2004 Oct 25;167(2):293-302.

Protein kinase associated with gating and closing transmission mechanisms in temporoammonic pathway.
Okada M, Zhu G, Yoshida S, Hirose S, Kanaeko S.
Neuropharmacology. 2004 Sep; 47(4)485-504.

Synaptic plasticity preserved with arachidonic acid diet in aged rats.
Susumu Kotani et al.
Neurosci Res. 2003 Aug;46(4):453-61.

Activity-evoked capacitative Ca2+ entry: implications in synaptic plasticity.
Baba A, Yasui T, Fujisawa S, Yamada RX, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
J Neurosci. 2003 Aug 27;23(21):7737-41.

A novel method for monitoring surface membrane trafficking on hippocampal acute slice preparation.
Thomas-Crusells J, Vieira A, Saarma M, Rivera C.
J Neurosci Methods 2003 May 30;125(1-2):159-66.

Age-dependent modulation of hippocampal excitability by KCNQ-channels.
Okada M, Zhu G, Hirose S, Ito KI, Murakami T, Wakui M, Kaneko S.
Epilepsy Res. 2003 Feb;53(1-2):81-94.

Mossy fibre synaptic NMDA receptors trigger non-Hebbian long-term potentiation at entorhino-CA3 synapses in the rat.
Tsukamoto M, Yasui T, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
J Physiol. 2003 Feb 1;546(Pt 3):665-75.

Asymmetrical distribution of the Schaffer projections within the apical dendrites of hippocampal field CA1.
Shimono K, Kubota D, Brucher F, Taketani M, Lynch G.
Brain Res. 2002 Sep 20;950(1-2):279-87.

Impaired M-current and neuronal excitability.
Okada M, Wada K, Kamata A, Murakami T, Zhu G, Kaneko S.
Epilepsia 2002 Jun;43 Suppl 9:36-8.

Continuous two-dimensional current source density analyses of electrophysiological activity in hippocampal slices.
Shimono K, Taketani M, Brucher F, Kubota D, Colgin L, Robertson S, Granger R, Lynch G.
Neurocomputing. 2001 Jun;38-40:899-905.

Origins and distribution of cholinergically induced beta rhythms in hippocampal slices.
Ken Shimono et. al (2000).
J Neurosci. 2000 Nov 15;20(22):8462-73.

Dysfunction of M-channel enhances propagation of neuronal excitability in rat hippocampus monitored by multielectrode dish and microdialysis systems.
Gang Zhu et. al. (2000).
Neurosci Lett. 2000 Nov 10;294(1):53-7.

A new planar multielectrode array for extracellular recording: application to hippocampal acute slice.
Oka H, Shimono K, Ogawa R, Sugihara H, Taketani M.
J Neurosci Methods. 1999 Oct 30;93(1):61-7.

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