MED64 multi-electrode array system
A complete, user-friendly solution for in-vitro electrophysiology
based on planar microelectrode technology.
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Cardiac Myocyte Cultures



Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs.                                     NEW!
Otsuji TG, Minami I, Kurose Y, Yamauchi K, Tada M, Nakatsuji N.
Stem Cell Res. 2010 Feb 6



The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells.
 Yokoo N, Baba S, Kaichi S, Niwa A, Mima T, Doi H, Yamanaka S, Nakahata T, Heike T.
Biochem Biophys Res Commun. 2009 Sep 25;387(3):482-8.    



In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
. Tanaka T, Tohyama S, Murata M, Nomura F, Kaneko T, Chen H, Hattori F, Egashira T, Seki T, Ohno Y, Koshimizu U, Yuasa S, Ogawa S, Yamanaka S, Yasuda K, Fukuda K.
Biochem Biophys Res Commun. 2009 Aug 7;385(4):497-502.  



Effects of Aldosterone on Cx43 Gap Junction Expression in Neonatal Rat Cultured Cardiomyocytes.
Suzuki S, Ohkusa T, Sato T, Yoshida M, Yasui K, Miwa K, Lee JK, Yano M, Kodama I, Matsuzaki M.
Circ J. 2009 Jun 16. [Epub ahead of print]



Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells.
Kado M, Lee JK, Hidaka K, Miwa K, Murohara T, Kasai K, Saga S, Morisaki T, Ueda Y, Kodama I.
Biochem Biophys Res Commun. 2008 Dec 12;377(2):413-8. Epub 2008 Oct 18.

T-type Ca2+ channel blockers prevent cardiac cell hypertrophy through an inhibition of calcineurin-NFAT3 activation as well as L-type Ca2+ channel blockers.
Horiba M, Muto T, Ueda N, Opthof T, Miwa K, Hojo M, Lee JK, Kamiya K, Kodama I, Yasui K.
Life Sci. 2008 Mar 12;82(11-12):554-60. Epub 2007 Dec

lectrical coupling of cardiomyocyte sheets occurs rapidly via functional gap junction formation. Biomaterials
Haraguchi Y, Shimizu T, Yamato M, Kikuchi A, Okano T.
Biomaterials.2006 Sep;27(27):4765-74. Epub 2006 Jun 5

Tissue cardiomyoplasty using bioengineered contractile cardiomyocyte sheets to repair damaged myocardium: their integration with recipient myocardium.
Miyagawa S, Sawa Y, Sakaida S, Taketani S,Kondoh H, Memon IA, Imanishi Y, Shimizu T, Okano T, Matsuda H.
Transplantation. 2005 Dec 15;80(11):1586-95

Conduction abnormality in gap junction protein connexin45-deficient embryonic stem cell-derived cardiac myocytes.
Egashira K, Nishii K, Nakamura K, Kumai M, Morimoto S, Shibata Y
Anat Rec 2004 Oct;280A(2):973-9.

Rapid electrical stimulation of contraction modulates gap junction protein in neonatal rat cultured cardiomyocytes: involvement of mitogen-activated protein kinases and effects of angiotensin II-receptor antagonist.
Inoue N, Ohkusa T, Nao T, Lee JK, Matsumoto T, Hisamatsu Y, Satoh T, Yano M, Yasui K, Kodama I, Matsuzaki M
J Am Coll Cardiol 2004 Aug 18;44(4):914-22.

 

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