A low-noise multi-electrode array system for
in vitro extracellular electrophysiology

MED64 System

MED Probe

MED64 Amplifier

MED Connector

Software

Key Technologies

MED64 SOFTWARE

Evoked Potential Measurement Package
Spike Sorter
Mobius QT

MED64 Mobius – Spike Sorter

For Recording and Analysis of spikes from brain slices or neuronal cultures


Display for acquisition control panel and all 64 channels


Display for Spike Sorting: Thresholds are set in the left-top chart. Detected spikes (middle-left) are extracted and sorted (middle-right), and analyzed for frequency (bottom). The result for other channels can be displayed by selecting the channel of interest in the bottom-left channel selector.

 

 

Acquisition

  • Spontaneous signals are recorded at all 64 channels according to user-defined acquisition parameters.
  • Acquisition parameters are set easily in a simple control panel.

Analysis

  • Spikes exceeding user-defined thresholds are automatically extracted and can be sorted based on waveform similarity at all 64 channels.
  • Spike frequency is computed and graphed for each channel.
  • Averages and standard deviations for spike frequencies on all 64 channels can be automatically computed and graphed for each user-defined experiment phase. Useful for making multi-step dose-response curves.

Data Output

  • Spike time-stamps, waveforms of extracted spikes, and spike frequency charts can be saved in ASCII text file (csv) format, even WITHOUT saving raw data.
  • Raw data can be exported to binary or ASCII text file (csv) formats.
 

Spike frequency analysis without spike sorting:

Thresholds are set in the left-top chart. Detected spikes (middle-left) are extracted and their waveforms are displayed (middle-right). Spike frequency is analyzed for all extracted spikes at a channel (bottom). The result for another channels can be obtained by selecting the channel at the channel selector.


 
 

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Alpha MED Scientific Inc., 209 Saito-incubator, 7-7-15, Saito-asagi, Ibaraki Osaka, 567-0085, Japan