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A low-noise multi-electrode array system for in vitro extracellular electrophysiology |
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MED PROBE
MED Probe |
Multi-electrode array with the industry’s lowest impedance electrodes. Acute or cultured biological preparations are placed or grown directly on a grid of 64 planar microelectrodes, with the capability for stimulation and signal recording. The standard MED probe has 64 planar microelectrodes arranged in an 8 x 8 grid embedded in the center of a transparent glass plate. The surrounding glass or plastic cylinder makes the MED probe a self-contained recording chamber. Four models with inter-electrode spacings of 100, 150, 300, and 450µm enable detailed evaluation of network interactions across a sample. Each electrode is 50µm x 50µm in size for 150, 300, and 450µm spacing configuration, or 20µm x 20µm for 100µm spacing configuration. |
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| Also available are probes featuring an electrode pattern specific to hippocampus anatomy and a hexagonal pattern, as well as 2- and 4-well MED probes for increasing throughput.
The micro-planar electrodes patterned on the MED probe have the industry’s lowest impedance (10kΩ at 1 kHz for 50μm electrode) which results in superior signal-to-noise ratios. (Learn MORE about the technology and related benefits) |
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Standard 8x8 Arrays
Interpolar Distance of Electrodes |
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Product Number |
Array size |
Electrode size |
Recording Electrodes
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Reference Electrodes
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Chamber Depth
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MED-P2105 |
0.7x0.7mm |
20x20 µm |
100 µm
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8.5 mm |
5 mm
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MED-P210A |
0.7x0.7mm |
20x20 µm |
100 µm
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8.5 mm |
10 mm
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MED-P5155 |
1 x 1 mm |
50x50 µm |
150 µm
|
8.5 mm |
5 mm
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MED-P515A |
1 x 1 mm |
50x50 µm |
150 µm
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8.5 mm |
10 mm
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MED-P5305 |
2 x 2 mm |
50x50 µm |
300 µm
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9.2 mm |
5 mm
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MED-P530A |
2 x 2 mm |
50x50 µm |
300 µm
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9.2 mm |
10 mm
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MED-P5455 |
3 x 3 mm |
50x50 µm |
450 µm
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10.2 mm |
5 mm
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MED-P545A |
3 x 3 mm |
50x50 µm |
450 µm
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10.2 mm |
10 mm
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MED-P515A Close Up View
MED-P210# (0.7mm)
Mouse Hippocampus CA1 |
MED-P515# (1mm)
Mouse Hippocampus |
MED-P515# (1mm)
Rat Hippocampus CA1 |
MED-P530# (2mm)
Rat Hippocampus |
MED-P545# (3mm)
Rat Hippocampus and Peripheral area |
Hippocampal Pattern Arrays (CA1, CA3, & DG)
Interpolar Distance of Electrodes |
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Parts number |
Electrode size |
Recording electrodes |
Reference electrodes |
Chamber Depth |
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MED-P50015 |
For Rat |
ø 50 µm |
150 µm |
8.5 mm |
5 mm |
MED-P5001A |
For Rat |
ø 50 µm |
150 µm |
8.5 mm |
10 mm |
MED-P50025 |
For Mouse |
ø 50 µm |
150 µm |
8.5 mm |
5 mm |
MED-P5002A |
For Mouse |
ø 50 µm |
150 µm |
8.5 mm |
10 mm |
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| MED-P5001A Micrograph of rat hippocampal slice and arrangement of microelectrodes. Click to zoom. |
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| MED-P5002A Micrograph of rat hippocampal slice and arrangement of microelectrodes. Click to zoom. |
Hexagonal Arrays (61 Electrodes)
Interpolar Distance of Electrodes |
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Product Number |
Electrode size |
Recording electrodes |
Reference electrodes |
Chamber Depth |
MED-P2H075 |
ø 50 µm |
70 µm |
8.5 mm |
5 mm |
MED-P2H07A |
ø 50 µm |
70 µm |
8.5 mm |
10 mm |
MED-P2H07A
Close up view and arrangement of microelectrodes. Click to zoom.
MED probes for Parallel Sample Processing
2-Sample MED probe
2- Sample MED Probe (2-well type, MED-P5D15A) (left) and schematic diagram of microelectrode pattern (right).
Product Number |
Number of wells |
Electrode size |
Inter-polar distance (The smallest) |
Distance between electrode blocks |
Chamber
Depth |
Partition-
height |
MED-P50035 |
1 |
ø 50 µm |
150 µm |
12 mm |
5 mm |
NA |
MED-P5003A |
1 |
ø 50 µm |
150 µm |
12 mm |
10 mm |
NA |
MED-P5D15A |
2 |
ø 50 µm |
150 µm |
NA |
10 mm |
10 mm |
MED-P5D15B |
2 |
ø 50 µm |
150 µm |
NA |
10 mm |
5 mm |
4-Sample MED probe
4- Sample MED Probe (4-well type, MED-P5FF15) (left) and schematic diagram of microelectrode pattern (right)
Product Number |
Number of wells |
Electrode Size |
Inter-polar distance (The smallest) |
Distance between electrode blocks |
Chamber Depth |
Partition- height |
MED-P50045 |
1 |
ø 50 µm |
150 µm |
5.5 |
5 mm |
NA |
MED-P5004A |
1 |
ø 50 µm |
150 µm |
5.5 |
10 mm |
NA |
MED-P5DF15 |
2 |
ø 50 µm |
150 µm |
NA |
10 mm |
10 mm |
MED-P5FF15 |
4 |
ø 50 µm |
150 µm |
NA |
10 mm |
10 mm |
Specifications
| Substrate | |
| Glass substrate: | 50 x 50 x 0.7mm |
| Glass cylindrical chamber: | ID=22, OD=25mm |
| Conducting layer: | Indium tin oxide (ITO) ( 0.15µm) |
| Insulation layer: | Polyacrylamide (1.5µm) |
| Recording / Stimulating electrodes | |
| Material | ITO + Platinum Black |
| Impedance | < 22kΩ (Typical:10Ω) for 50µm electrodes |
| < 40kΩ (Typical : 30Ω) for 20µm electrodes | |
| (1kHz, 50mV applied sinusoidal wave) | |
| Reference electrodes | |
| Material | ITO + Platinum Black |
| Size | 200 x 200µm |
| ø 100µm x 4 (MED-P2H07#, MED-P500##, MED-P5D###, MED-P5F###) |
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