MED64 multi-electrode array system
A complete, user-friendly solution for in-vitro electrophysiology
based on planar microelectrode technology.
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Applications
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  Synaptic Activity
  Biological Rythms
  Pharmacology and Drug Testing
  Unit and Network Activity
  Muscle Propagation and Pacing
  Combining with Other Equipment

  Preparation Based Applications

MED64 Applications

The MED64 system is well suited for experiments using acute slices as well as slice (and cell) cultures. The low impedance of of Pt. black electrodees (7-10 khom at 1 kHz tycpially) enables to acquire several types of signals (from slow-wave to spike signals) easily.

Multi-electrode arrays are widely used in studies of the central (CNS: e.g. Cortex, Hippocampus; retina, Suprachiasmatic Nucleus, SCN) and peripheral (PNS: e.g. Dorsal Root Ganglion, DRG) nervous system, as well as myocardial and other excitable tissue (e.g. smooth muscle). Extracellular stimulation and recording can be combined with patch clamping, microscopic visualization, or other methods (e.g. Ca ++ imaging) used to examine relationships between structure and function.

Experimental Examples

1) Studies on Synaptic Activity
LTP | CSD

2) Studies of Biological Rhythms

Spontaneous Rhythmic Activities

3) Pharmacology and Drug Testing
Toxicology

4) Unit and Network Activity
Spike Sorting and Determination

5) Muscle Propagation & Pacing
Examples
 
6) QT Prolongation

Click on the individual pictures or characters to obtained detailed examples or publications of a selection of various slice and culture preparations that have been studied with the MED64 System.
 
Visit Resource page for publications of each preparation.
 
  CNS / PNS Myocardium and Smooth Muscle

Acute Slices

  Hippocampus  
Cortex
Atrium Ventricular Slice
 
Hypothalamus
SCN Smooth Muscle  
Spinal Cord

  Amygdala.
  Substantia nigra.
  Superior Colliculus.
  Brain stem.
   Retina.   
   and MORE.
   

   
Slice Cultures Hippocampal Slice SCN Slice
 
Slice Co-Cultures

 
        Cerebellum 
        Cortex

   
Dissociated Cultures DRG Cells

Hippocampus.  Cortex.
Cerebellum.
SCN.
and MORE.
 

 
Myocardial cells

 


iPS cells

ES cells

       

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