The MED64 system is well suited for experiments using acute slices as well as slice (and cell) cultures. The low impedance of of Pt. black electrodees (7-10 khom at 1 kHz tycpially) enables to acquire several types of signals (from slow-wave to spike signals) easily.
Multi-electrode arrays are widely used in
studies of the central (CNS: e.g. Cortex, Hippocampus; retina,
Suprachiasmatic Nucleus, SCN) and peripheral (PNS: e.g. Dorsal
Root Ganglion, DRG) nervous system, as well as myocardial and
other excitable tissue (e.g. smooth muscle). Extracellular
stimulation and recording can be combined with patch clamping,
microscopic visualization, or other methods (e.g. Ca ++
imaging) used to examine relationships between structure and
function.
6) QT Prolongation
Examples
Click on
the individual pictures to obtained detailed examples of a
selection of various slice and culture preparations that have
been studied with the MED64 System.
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